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What are the recommended antiviral medications for the first clinical episode of genital herpes according to Collins-Bride & Saxe's Clinical Guidelines?

The recommended antiviral medications for the first clinical episode of genital herpes are Acyclovir 400 mg orally three times a day, Famciclovir 250 mg orally three times a day, or Valacyclovir 1 gm orally twice a day, all for 7 to 10 days.

For the first clinical episode of genital herpes, the recommended antiviral medications include Acyclovir, Famciclovir, and Valacyclovir. Acyclovir should be taken at a dose of 400 mg orally three times a day. Famciclovir is recommended at 250 mg orally three times a day. Valacyclovir should be administered at 1 gm orally twice a day. Each of these treatments is typically prescribed for a duration of 7 to 10 days, and the treatment can be extended if healing is incomplete after 10 days.

Key points

  • Acyclovir 400 mg orally 3×/day for 7–10 days.
  • Famciclovir 250 mg orally 3×/day for 7–10 days.
  • Valacyclovir 1 gm orally 2×/day for 7–10 days.
  • Treatment duration is typically 7 to 10 days.
  • Treatment can be extended if healing is incomplete after 10 days.
Source:Collins-Bride & Saxe’s Clinical Guidelines for Advanced Practice Nursing· Herpes Simplex Virus· p. 1235–1241
Cover of Collins-Bride & Saxe’s Clinical Guidelines for Advanced Practice Nursing

Collins-Bride & Saxe’s Clinical Guidelines for Advanced Practice Nursing

Joo, Yoonmee;Gatewood, J. V.;Israel, Mary Anne M.;Wong McGrath, Kelly;

FOURTH EDITION · Jones & Bartlett Learning

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