What are the two most important non-remediable risk factors for atherosclerosis in older adults?

The two most important non-remediable risk factors for atherosclerosis in older adults are advanced age and male gender.

Atherosclerosis in older adults is influenced by several risk factors, some of which can be modified and others that cannot. Among the non-remediable risk factors, advanced age and male gender are considered the most significant. These factors are inherent and cannot be altered through lifestyle changes or medical interventions, unlike other risk factors such as high blood pressure, cholesterol levels, and smoking, which can be managed to reduce the risk of atherosclerosis.