What are the injection points and doses for botulinum toxin treatment of axillary hyperhidrosis?

For treating axillary hyperhidrosis with botulinum toxin, 45-50 units of onabotulinumtoxinA (OBTX) are injected per axilla. The treatment involves 20 injection points per axilla, with each point receiving 2.5 units of OBTX.

In the treatment of axillary hyperhidrosis using botulinum toxin, the recommended dose is 45-50 units of onabotulinumtoxinA (OBTX) per axilla. The procedure involves marking 20 evenly distributed injection points per axilla, each spaced 1.5-2 cm apart. At each of these points, 2.5 units of OBTX are injected intradermally. The injections are performed using a 30-gauge, 0.5-inch needle, angled at 45 degrees to the skin surface, with the needle tip inserted just under the skin to a depth of approximately 2 mm to raise a wheal. This method aims to significantly reduce or completely stop underarm sweating, with effects typically noticeable 1-2 weeks post-treatment and lasting around 6 months.